What is Methadone?

 
 
 
 
Methadone
   
 
  • Methadone is a narcotic pain reliever, similar to morphine
  • Legally authorized opioid used to treat Heroin addiction
  • Methadone is not as intense as Heroin…though it too is addictive
  • Suppresses narcotic withdrawal for between 24 and 36 hours
  • Because methadone is effective in eliminating withdrawal symptoms, it is used in detoxifying opiate addicts
  • Reduces the cravings associated with heroin use and blocks the high from heroin, but it does not provide the euphoric rush
  • Ultimately, the patient remains physically dependent on the opioid, but is freed from the uncontrolled, compulsive, and disruptive behavior seen in heroin addicts.

Street Names

  • Juice, dollies, amidone, fizzies

Who Uses Methadone?

  • Most people being treated for dependence on opioid drugs
  • People who are dependent on illicit opioids, such as heroin, and also prescription opioids, such as codeine
  • Women who use opioid drugs regularly and who are pregnant are often treated with methadone to protect the fetus.
  • Methadone maintenance, combined with medical care, improves the chances of having a healthy baby.
  • Methadone is sometimes used to provide pain relief for people who have severe chronic pain or pain associated with terminal illness.

Routes of Administration

  • Methadone is available with a prescription under the brand names
    • Dolophine and Methadose
  • Orally
  • Tablets
  • Dispersible tablets
  • Oral solution (liquid)  
  • Injection

Signs & Symptoms of Use

  • constipation
  • water retention
  • drowsiness
  • skin rash
  • excessive sweating
  • and changes in libido
  • feeling anxious
  • nervous
  • or restless
  • sleep problems-insomnia
  • feeling weak or drowsy
  • dry mouth
  • nausea
  • vomiting
  • diarrhea
  • constipation
  • loss of appetite
  • decreased sex drive

Short - Term Effects

  • Painkilling and depressing effects
  • Can slow breathing
  • Hallucinations
  • Confusion
  • Chest pain
  • Dizziness
  • Fainting
  • Fast or pounding heartbeat
  • Trouble breathing
  • Feeling light-headed
  • Fainting
  • Constipation
  • Nausea
  • Vomiting
  • Sedation
  • Vertigo
  • Edema
  • Impotence

Symptoms of Methadone Withdrawal?


Many former heroin users have claimed that the horrors of heroin withdrawal were far less painful and difficult than withdrawal from methadone.
Methadone withdrawal symptoms include but are not limited to:

  • sneezing
  • yawning
  • tearing of eyes
  • runny nose
  • excessive perspiration
  • fever
  • dilated pupils
  • abdominal cramps
  • nausea
  • body aches
  • tremors
  • irritability

Long - Term Effects

  • DEATH
  • What are the symptoms of methadone overdose?
    • Body as a whole
      • muscle spasticity
    • Respiratory
      • difficulty breathing
      • slow, shallow and labored breathing
      • stopped breathing (sometimes fatal within 2-4 hours)
    • Eyes, ears, nose and throat
      • pinpoint pupils
      • bluish skin
      • bluish fingernails and lips
    • Gastrointestinal
      • spasms of the stomach and/or intestinal tract
      • constipation
    • Heart and blood vessels
      • weak pulse
      • low blood pressure
    • Nervous system
      • Drowsiness
      • Disorientation
      • coma
  • anaphylactic reactions
  • hypertension causing weakness and fainting
  • disorientation
  • hallucinations
  • unstable gait
  • tremor
  • muscle twitching
  • myasthenia gravis
  • kidney failure
  • seizures

Buprenorphine

  • Methadone or buprenorphine may be used for OxyContin addiction treatment or, for that matter, treatment for addiction to any other opiod, including the semisynthetic opioids.

References:

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